KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation

Summary: Oncogenic KRAS mutations are prevalent in colorectal cancer (CRC) and linked to poor prognosis and therapeutic resistance. Emerging evidence suggests that specific KRAS mutations differentially influence treatment responses. In this study, we generate isogenic Apc-null mouse colon epithelia...

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Hlavní autoři:	Konstantin Budagyan, Alexa C. Cannon, Adam Chatoff, Dorothy Benton, Alison M. Kurimchak, Daniela Araiza-Olivera, Anastasiia Gerasimova, Nathaniel W. Snyder, James S. Duncan, Cristina Uribe-Alvarez, Jonathan Chernoff
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-04-01
Edice:	Cell Reports
Témata:	CP: Cancer
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124725002153
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