Artemether resistance <it>in vitro</it> is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with <it>Plasmodium falciparum</it> infections

<p>Abstract</p> <p>Background</p> <p>Monitoring resistance phenotypes for <it>Plasmodium falciparum</it>, using <it>in vitro</it> growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins.</p> <p>Methods</p> <p><it>Plasm...

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Autori principali:	Pillai Dylan R, Lau Rachel, Khairnar Krishna, Lepore Rosalba, Via Allegra, Staines Henry M, Krishna Sanjeev
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2012-04-01
Serie:	Malaria Journal
Soggetti:	Artemisinin resistance <it>pfmdr1</it> <it>pfatp6</it> Gene copy number Malaria Travellers <it>Plasmodium</it>
Accesso online:	http://www.malariajournal.com/content/11/1/131
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