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Review: Progress of the NLRP3 inflammasome in tumours and perspectives for cholangiocarcinoma

Abstract The NLRP3 inflammasome is a multi-protein complex that mediates intense inflammatory responses. Its activation and function are influenced by various factors, including the recognition of pathogen-associated molecular patterns and damage-associated molecular patterns, cellular stress respon...

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Principais autores: Zhaoqin Zhuo, Yuwei Xie, Hao Zou, Bin Tan, Qian Dong, Bingzi Dong, Chengzhan Zhu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-10-01
Serier:Cell Communication and Signaling
Fag:
NLRP3 inflammasome
Cholangiocarcinoma
Tumour
Inflammation and cancer transformation
Online adgang:https://doi.org/10.1186/s12964-025-02416-4
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