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Therapeutic potential of TNFR2 agonists: a mechanistic perspective

TNFR2 agonists have been investigated as potential therapies for inflammatory diseases due to their ability to activate and expand immunosuppressive CD4+Foxp3+ Treg cells and myeloid-derived suppressor cells (MDSCs). Despite TNFR2 being predominantly expressed in Treg cells at high levels, activated...

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Bibliografiske detaljer
Principais autores: Yibo Chen, Mengmeng Jiang, Xin Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-08-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1209188/full
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