Polydeoxyribonucleotide ameliorates IL-1β-induced impairment of chondrogenic differentiation in human bone marrow-derived mesenchymal stem cells

Abstract Osteoarthritis (OA) is a degenerative disease of the joints, prevalent worldwide. Polydeoxyribonucleotide (PDRN) is used for treating knee OA. However, the role of PDRN in IL-1β-induced inflammatory responses in human bone marrow-derived mesenchymal stem cells (hBMSCs) remains unknown. Here...

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Detalles Bibliográficos

Principais autores:	Ahreum Baek, Dawoon Baek, Sung Hoon Kim, Jinyoung Kim, Geneva Rose Notario, Do‑Won Lee, Hyun Jung Kim, Sung-Rae Cho
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2024-10-01
Series:	Scientific Reports
Assuntos:	Polydeoxyribonucleotide Mesenchymal stem cell Chondrogenic differentiation Interleukin-1β Osteoarthritis
Acceso en liña:	https://doi.org/10.1038/s41598-024-77264-2
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