Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction

Abstract Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role in the heart is unknown. We have demonstrated, using single cell RNA-seq, that fibulin-...

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Detalhes bibliográficos

Principais autores:	Lucy A. Murtha, Sean A. Hardy, Nishani S. Mabotuwana, Mark J. Bigland, Taleah Bailey, Kalyan Raguram, Saifei Liu, Doan T. Ngo, Aaron L. Sverdlov, Tamara Tomin, Ruth Birner-Gruenberger, Robert D. Hume, Siiri E. Iismaa, David T. Humphreys, Ralph Patrick, James J. H. Chong, Randall J. Lee, Richard P. Harvey, Robert M. Graham, Peter P. Rainer, Andrew J. Boyle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2023-09-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-023-41894-9
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