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Single-Cell RNA Sequencing Reveals Cardiac Fibroblast-Specific Transcriptomic Changes in Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is the most common cause of heart failure, with a complex aetiology involving multiple cell types. We aimed to detect cell-specific transcriptomic alterations in DCM through analysis that leveraged recent advancements in single-cell analytical tools. Single-cell RNA sequ...

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Gardado en:
Principais autores: Adam Russell-Hallinan, Oisín Cappa, Lauren Kerrigan, Claire Tonry, Kevin Edgar, Nadezhda Glezeva, Mark Ledwidge, Kenneth McDonald, Patrick Collier, David A. Simpson, Chris J. Watson
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2024-04-01
Series:Cells
Assuntos:
heart failure
dilated cardiomyopathy
cardiac fibroblasts
single-cell RNA sequencing
Acceso en liña:https://www.mdpi.com/2073-4409/13/9/752
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