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Focal adhesion kinase: from biological functions to therapeutic strategies

Abstract Focal adhesion kinase (FAK), a nonreceptor cytoplasmic tyrosine kinase, is a vital participant in primary cellular functions, such as proliferation, survival, migration, and invasion. In addition, FAK regulates cancer stem cell activities and contributes to the formation of the tumor microe...

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Principais autores: Ximin Tan, Yuheng Yan, Bin Song, Shuangli Zhu, Qi Mei, Kongming Wu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-09-01
Serier:Experimental Hematology & Oncology
Fag:
Focal adhesion kinase
Immunotherapy
Combination therapy
Tumor microenvironment
Online adgang:https://doi.org/10.1186/s40164-023-00446-7
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