Nitazoxanide Modulates Mitochondrial Function and Inflammatory Metabolism in Chondrocytes from Patients with Osteoarthritis via AMPK/mTORC1 Signaling

Osteoarthritis (OA) is a long-term degenerative condition of the joints, characterized by persistent inflammation, progressive cartilage breakdown, and impaired mitochondrial function. Recent studies have shown that hyperactivation of the mTORC1 pathway and metabolic reprogramming of chondrocytes co...

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Autores principales:	Ha Eun Kim, Jong Yeong Lee, Ga-Yeon Son, Jun-Young Park, Ki Bum Kim, Chul-Min Choi, Young Jae Moon, Jin Kyeong Choi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2025-04-01
Colección:	Antioxidants
Materias:	nitazoxanide osteoarthritis chondrocytes AMPK mTORC1 mitochondrial dysfunction
Acceso en línea:	https://www.mdpi.com/2076-3921/14/5/512
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