Dihydrotanshinone as a Natural Product-Based CYP17A1 Lyase Inhibitor for Hyperandrogenic Disorders
Selective inhibition of CYP17A1 17,20-lyase is critical for treating hyperandrogenic disorders without the cortisol-depleting side effects of non-selective drugs like abiraterone. We evaluated tanshinones from <i>Salvia miltiorrhiza</i> as potential selective inhibitors using biochemical assays and...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2026-01-01
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| Serie: | Biomolecules |
| Soggetti: | |
| Accesso online: | https://www.mdpi.com/2218-273X/16/1/144 |
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