NV716 acts as an envelope-active adjuvant that enhances antibiotic accumulation in Pseudomonas aeruginosa

Abstract Treatment of Gram-negative infections remains challenging due to limited compound penetration and the presence of efflux mechanisms. Pseudomonas aeruginosa, in particular, exhibits strong intrinsic resistance, leaving few effective therapeutic options. Here, we provide mechanistic insight i...

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Egile Nagusiak:	Margot Draveny, Hugo Chauvet, Axelle De Pauw, Valérie Rouam, Harisa Rista, Pierre Legrand, Marine Novelli, Jean-Michel Bolla, Maria Girleanu, Anne-Laure Favier, Fabienne Neulat-Ripoll, Jean-Michel Brunel, Frédéric Jamme, Muriel Masi
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2026-04-01
Saila:	npj Antimicrobials and Resistance
Sarrera elektronikoa:	https://doi.org/10.1038/s44259-026-00203-w
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