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Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

Microbial secondary metabolites are a rich source for pharmaceutical discoveries and play crucial ecological functions. While tools exist to identify secondary metabolite clusters in genomes, precise sequence-to-function mapping remains challenging because neither function nor substrate specificity...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Shaohua Gu, Yuanzhe Shao, Karoline Rehm, Laurent Bigler, Di Zhang, Ruolin He, Ruichen Xu, Jiqi Shao, Alexandre Jousset, Ville-Petri Friman, Xiaoying Bian, Zhong Wei, Rolf Kümmerli, Zhiyuan Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: eLife Sciences Publications Ltd 2024-10-01
Rangatū:eLife
Ngā marau:
microbial secondary metabolites
siderophore
pyoverdine
genome mining
non-ribosomal peptide synthetases
Pseudomonas
Urunga tuihono:https://elifesciences.org/articles/96719
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