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Network pharmacology-based investigation and experimental validation of the mechanism of metformin in the treatment of acute myeloid leukemia

Abstract Metformin, a widely used anti-diabetic agent, has shown significant anti-cancer properties as reported in in various cancers, including acute myeloid leukemia. However, the detailed mechanisms by which metformin influences acute myeloid leukemia remain unrevealed. Employing a synergistic ap...

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Bibliografiske detaljer
Principais autores: Shaoyu Liu, Mingming Xu, Zhuofan Yang, Yangzi Li, Depei Wu, Xiaowen Tang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-09-01
Serier:European Journal of Medical Research
Fag:
Online adgang:https://doi.org/10.1186/s40001-024-02022-z
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