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Role of AMPK-SREBP Signaling in Regulating Fatty Acid Binding-4 (FABP4) Expression following Ethanol Metabolism

Fatty acid binding protein-4 (<i>FABP4</i>) is not normally expressed in the liver but is induced in alcohol-dependent liver disease (ALD)). This study sought to identify mechanisms whereby ethanol (EtOH) metabolism alters triglyceride accumulation and <i>FABP4</i> production. Human hepatoma cells w...

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Main Authors: Neha Attal, Emilio Marrero, Kyle J. Thompson, Iain H. McKillop
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-11-01
Series:Biology
Subjects:
alcohol
liver disease
cytochrome P4502E1
SREBP-1c
AMPKα
fatty acid binding protein
Online Access:https://www.mdpi.com/2079-7737/11/11/1613
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