Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis
Abstract Necroptosis and ferroptosis are two distinct forms of necrotic-like cell death in terms of their morphological features and regulatory mechanisms. These two types of cell death can coexist in disease and contribute to pathological processes. Inhibition of both necroptosis and ferroptosis ha...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Nature Publishing Group
2024-10-01
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| Ráidu: | Cell Death and Disease |
| Liŋkkat: | https://doi.org/10.1038/s41419-024-07157-9 |
| Fáddágilkorat: |
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