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Twenty-Four-Hour Heart Rate Is a Trait but Not State Marker for Depression in a Pilot Randomized Controlled Trial With a Single Infusion of Ketamine

Background: Abnormalities of heart rate (HR) and its variability are characteristic of major depressive disorder (MDD). However, circadian rhythm is rarely taken into account when statistically exploring state or trait markers for depression.Methods: A 4-day electrocardiogram was recorded for 16 tre...

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Principais autores: Carmen Schiweck, Erika Lutin, Walter De Raedt, Olivia Cools, Violette Coppens, Manuel Morrens, Chris Van Hoof, Elske Vrieze, Stephan Claes
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-07-01
Serier:Frontiers in Psychiatry
Fag:
heart rate
depression
heart rate variability
circadian rhythm
ketamine
biomarker
Online adgang:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.696170/full
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