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Altered gut microbial diversity, composition, and metabolomic potential in patients with major depressive disorder and recent suicide attempt

This study investigates the role of the gut microbiome in suicidal behavior among individuals with major depressive disorder (MDD). Fecal samples from 50 hospitalized patients with MDD, including 35 with recent suicide attempts (60 % female) and 15 without a history of suicide (73 % female), were an...

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Principais autores: Emese Prandovszky, Hua Liu, Emily G. Severance, Victor W. Splan, Faith B. Dickerson, Robert H. Yolken
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-10-01
Serier:Brain, Behavior, & Immunity - Health
Fag:
Recent suicide attempt
Microbiome
Shotgun sequencing
Metabolomic profiling
Gut-brain axis
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666354625001395
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