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Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes

(1) Background: Disruption of insulin production by native or transplanted pancreatic islets caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and important therapeutic challenge due to the lifelong need for exogeneous insulin administration. Early metabolic biomarkers...

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Principais autores: Oscar Alcazar, Luis F. Hernandez, Ashley Tschiggfrie, Michael J. Muehlbauer, James R. Bain, Peter Buchwald, Midhat H. Abdulreda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-09-01
Colecção:Metabolites
Assuntos:
autoimmune diabetes
anterior chamber of the eye
gender differences
non-obese diabetic (nod) mice
pancreatic islet
local metabolomics
non-targeted metabolomics
gc-ms
islet microenvironment
t1d biomarkers
Acesso em linha:https://www.mdpi.com/2218-1989/9/10/207
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