Transcriptome of monocytes from liver, brain and bone marrow reveals organ-specific features in aging and alcohol misuse

Background & Aims: Aging and alcohol misuse independently alter monocyte (MO) and macrophage (MØ) function, leading to impaired antimicrobial responses. However, how alcohol misuse contributes to impaired MO/MØ function during aging remains unclear. Methods: We compared the transcriptomes of MOs...

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Autors principals:	Martí Ortega-Ribera, Radhika Joshi, Sergi Guixé-Muntet, Veronika Brezani, Prashanth Thevkar Nagesh, Viliam Brezani, Arman Patel, Yuan Zhuang, Mrigya Babuta, Jordi Gracia-Sancho, Gyongyi Szabo
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-12-01
Col·lecció:	JHEP Reports
Matèries:	macrophage microglia interferon communication multi-organ ethanol
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S258955592500285X
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