Quantitative detection of T315I mutations of BCR::ABL1 using digital droplet polymerase chain reaction

Background: T315I mutations of the BCR::ABL1 gene lead to resistance to tyrosine kinase inhibitors (TKIs). This study evaluated the performance of digital droplet polymerase chain reaction (ddPCR) in quantifying T315I mutations and their frequency in Philadelphia chromosome (Ph) positive hematologic...

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Bibliografiska uppgifter

Huvudupphov:	Huijun Mu, Jian Zou, Haiping Zhang
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2024-12-01
Serie:	Hematology, Transfusion and Cell Therapy
Ämnen:	BCR::ABL1 gene T315I mutation Digital droplet polymerase chain reaction Philadelphia chromosome
Länkar:	http://www.sciencedirect.com/science/article/pii/S2531137924000300
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