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Adoptive transfer of allergen-expressing B cells prevents IgE-mediated allergy

IntroductionProphylactic strategies to prevent the development of allergies by establishing tolerance remain an unmet medical need. We previously reported that the transfer of autologous hematopoietic stem cells (HSC) expressing the major timothy grass pollen allergen, Phl p 5, on their cell surface...

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Principais autores: Lisa Prickler, Ulrike Baranyi, Konstantinos Mengrelis, Anna Marianne Weijler, Verena Kainz, Bernhard Kratzer, Romy Steiner, Jasmin Mucha, Elisa Rudoph, Nina Pilat, Barbara Bohle, Herbert Strobl, Winfried Franz Pickl, Rudolf Valenta, Birgit Linhart, Thomas Wekerle
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-11-01
coleção:Frontiers in Immunology
Assuntos:
allergy
prophylaxis
tolerance
cell therapy
chimerism
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286638/full
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