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Rare variants create synthetic genome-wide associations.

Genome-wide association studies (GWAS) have now identified at least 2,000 common variants that appear associated with common diseases or related traits (http://www.genome.gov/gwastudies), hundreds of which have been convincingly replicated. It is generally thought that the associated markers reflect...

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Autors principals: Samuel P Dickson, Kai Wang, Ian Krantz, Hakon Hakonarson, David B Goldstein
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-01-01
Col·lecció:PLoS Biology
Accés en línia:http://europepmc.org/articles/PMC2811148?pdf=render
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