Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
Summary: Janus kinases (JAKs) and their downstream STAT proteins play key roles in cytokine signaling, tissue homeostasis, and cancer development. Using a breast cancer model that conditionally lacks Janus kinase 1, we show here that JAK1 is essential for IL-6-class inflammatory cytokine signaling a...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2018-11-01
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| Col·lecció: | Cell Reports |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S221112471831667X |
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