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A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

NADPH-oxidases (NOXs) purposefully produce reactive-oxygen-species (ROS) and are found in most kingdoms of life. The seven human NOXs are each characterized by a specific expression profile and a fine regulation to spatio-temporally tune ROS concentration in cells and tissues. One of the best known...

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Hlavní autoři: Joana Reis, Marta Massari, Sara Marchese, Marta Ceccon, Friso S. Aalbers, Federica Corana, Sergio Valente, Antonello Mai, Francesca Magnani, Andrea Mattevi
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020-05-01
Edice:Redox Biology
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2213231720301269
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