Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates

Development of resistance to deployed antimalarial drugs is inevitable and needs prompt and continuous discovery of novel candidate drugs. Therefore, the antimalarial activity of 125 compounds from the Medicine for Malaria Ventures (MMV) pathogen box was determined. Combining standard IC50 and norma...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Haddijatou Mbye, Fatoumata Bojang, Fatou Kene Jaiteh, Aminata Jawara, Bekai Njie, Simon Correa, Umberto D'Alessandro, Alfred Amambua-Ngwa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-08-01
Schriftenreihe:	International Journal for Parasitology: Drugs and Drug Resistance
Schlagworte:	Plasmodium falciparum Malaria Medicine for Malaria Venture (MMV) Pathogen box Antimalarial drug susceptibility
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2211320723000209
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