Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant.

Long pentraxin 3 (PTX3) is a non-redundant component of the humoral arm of innate immunity. The present study was designed to investigate the interaction of PTX3 with Neisseria meningitidis. PTX3 bound acapsular meningococcus, Neisseria-derived outer membrane vesicles (OMV) and 3 selected meningococ...

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Autori principali:	Barbara Bottazzi, Laura Santini, Silvana Savino, Marzia M Giuliani, Ana I Dueñas Díez, Giuseppe Mancuso, Concetta Beninati, Marina Sironi, Sonia Valentino, Livija Deban, Cecilia Garlanda, Giuseppe Teti, Mariagrazia Pizza, Rino Rappuoli, Alberto Mantovani
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2015-01-01
Serie:	PLoS ONE
Accesso online:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0120807&type=printable
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