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Interleukin-1: from discovery to therapeutic targeting of the first cytokine

Interleukin-1 (IL-1) was the first cytokine to be discovered and remains one of the most instructive molecules in immunology, linking fundamental mechanisms of innate immune activation to human inflammatory disease and targeted therapy. While it was initially identified for its relationship to fever...

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Detalles Bibliográficos
Principais autores: Lori Broderick, Naotomo Kambe, Hal M. Hoffman
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-07-01
Series:Allergology International
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S1323893026000237
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