Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis

Abstract Background Meropenem dosing for septic critically patients is difficult due to pathophysiological changes associated with sepsis as well as supportive symptomatic therapies. A prospective single-center study assessed whether fluid retention alters meropenem pharmacokinetics and the achievem...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Renata Černá Pařízková, Jiřina Martínková, Eduard Havel, Petr Šafránek, Milan Kaška, David Astapenko, Jan Bezouška, Jaroslav Chládek, Vladimír Černý
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-07-01
coleção:	Critical Care
Assuntos:	Meropenem Pharmacokinetics Pharmacodynamics Critically ill patients Sepsis Fluid therapy
Acesso em linha:	https://doi.org/10.1186/s13054-021-03680-9
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!