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A cross-sectional study in healthy elderly subjects aimed at development of an algorithm to increase identification of Alzheimer pathology for the purpose of clinical trial participation

Abstract Background In the current study, we aimed to develop an algorithm based on biomarkers obtained through non- or minimally invasive procedures to identify healthy elderly subjects who have an increased risk of abnormal cerebrospinal fluid (CSF) amyloid beta42 (Aβ) levels consistent with the p...

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Main Authors: Samantha Prins, Ahnjili Zhuparris, Ellen P. Hart, Robert-Jan Doll, Geert Jan Groeneveld
Format: Artigo
Language:Inglês
Published: BMC 2021-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer
Preclinical AD
Clinical trial
Algorithm
CSF Aβ
Online Access:https://doi.org/10.1186/s13195-021-00874-9
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