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Combined transcriptomic and proteomic analyses define conserved host signatures during innate immune perturbations in DF-1 chicken fibroblasts

The interferon system, first discovered in chicken embryonated eggs, plays a pivotal role in defending vertebrates against pathogens, yet comprehensive multi-omics analyses of immune responses in avian species remain scarce. In this study, we employed an integrative approach combining RNA-Seq transc...

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Autors principals: Frederic Sorgeloos, Efstathios S. Giotis, Kate Heesom, Michael A. Skinner, Ian G. Goodfellow
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2026-05-01
Col·lecció:Frontiers in Cellular and Infection Microbiology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fcimb.2026.1813484/full
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