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Immunoglobulin-Related Fibroinflammatory Diseases of Uncertain Etiology—Polarized Isotype Switching Connects an Ancient with a Contemporary Disease

IgG4 is an unusual immunoglobulin (Ig) and is the least component of IgG in humans. It is often asymmetrical and heterobivalent with weak Fc (fragment crystallizable region)-dependent effector function and ineffective complement activation, thus playing an unclear role in immune functions. IgE is an...

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Autore principale: Chi Sing Ng
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2025-04-01
Serie:Lymphatics
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Accesso online:https://www.mdpi.com/2813-3307/3/2/10
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