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Intracellular A53T Mutant α-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration

Dendritic dysfunction is an early event in α-synuclein (α-syn) mediated neurodegeneration. Altered postsynaptic potential and loss of dendritic spines have been observed in different in vitro and in vivo models of synucleinopathies. The integration of newborn neurons into the hippocampus offers the...

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Bibliográfalaš dieđut
Váldodahkkit: Martin Regensburger, Judith Stemick, Eliezer Masliah, Zacharias Kohl, Beate Winner
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2020-11-01
Ráidu:Frontiers in Cell and Developmental Biology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fcell.2020.561963/full
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