Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19) that presents with varied clinical manifestations ranging from asymptomatic or mild infections and pneumonia to severe cases associated with cytokine storm, acute respiratory distress syndrome (AR...

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Autors principals:	Shanmuga Sundaram Mahalingam, Sangeetha Jayaraman, Adhvika Arunkumar, Holly M. Dudley, Donald D. Anthony, Carey L. Shive, Jeffrey M. Jacobson, Pushpa Pandiyan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-09-01
Col·lecció:	Frontiers in Immunology
Matèries:	aging IL-1b CD8 IFNγ cells + + CD4 IFN-γ immune senescence
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1231087/full
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