Efficacy and safety of pyronaridine–artesunate versus artemether–lumefantrine in the treatment of acute uncomplicated malaria in children in South-West Nigeria: an open-labelled randomized controlled trial

Abstract Background In Nigeria, declining responsiveness to artemether–lumefantrine (AL), the artemisinin-based combination therapy (ACT) of choice since 2005, has been reported. Pyronaridine–artesunate (PA) is a newer fixed-dose ACT recently prequalified by the WHO for the treatment of uncomplicate...

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Autors principals:	Catherine O. Falade, Adebola E. Orimadegun, Fiyinfoluwa I. Olusola, Obaro S. Michael, Oluwafunmibi E. Anjorin, Roland I. Funwei, Aduragbenro D. Adedapo, Abiola L. Olusanya, Bose E. Orimadegun, Olugbenga A. Mokuolu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-05-01
Col·lecció:	Malaria Journal
Matèries:	Randomized clinical trial Pyronaridine–artesunate Artemether–lumefantrine Efficacy and safety Uncomplicated malaria Nigeria
Accés en línia:	https://doi.org/10.1186/s12936-023-04574-7
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