The Crimean-Congo Hemorrhagic Fever Virus NSm Protein Is Dispensable for Growth In Vitro and Disease in Ifnar^-/- Mice

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tri-segmented, tick-borne nairovirus that causes disease of ranging severity in humans. The CCHFV M segment encodes a complex glycoprotein precursor (GPC) that undergoes extensive endoproteolytic cleavage, giving rise to two structural proteins (Gn...

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Principais autores:	Stephen R. Welch, Florine E. M. Scholte, Jessica R. Spengler, Jana M. Ritter, JoAnn D. Coleman-McCray, Jessica R. Harmon, Stuart T. Nichol, Sherif R. Zaki, Christina F. Spiropoulou, Eric Bergeron
格式:	Artigo
语言:	Inglês
出版:	MDPI AG 2020-05-01
丛编:	Microorganisms
主题:	CCHF Crimean-Congo hemorrhagic fever reporter virus fluorescent protein reporter Ifnar<sup>-/-</sup> Ifnar knockout mouse
在线阅读:	https://www.mdpi.com/2076-2607/8/5/775
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