Influence of Surface-Modification via PEGylation or Chitosanization of Lipidic Nanocarriers on In Vivo Pharmacokinetic/Pharmacodynamic Profiles of Apixaban

Nanostructured lipid carriers (NLCs) have been proven to significantly improve the bioavailability and efficacy of many drugs; however, they still have many limitations. These limitations could hinder their potential for enhancing the bioavailability of poorly water-soluble drugs and, therefore, req...

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Автори:	Mohamed F. Zaky, Taha M. Hammady, Shadeed Gad, Abdullah Alattar, Reem Alshaman, Ann Hegazy, Sawsan A. Zaitone, Mamdouh Mostafa Ghorab, Mohamed A. Megahed
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2023-06-01
Серія:	Pharmaceutics
Предмети:	apixaban nanostructured lipid carriers chitosanization PEGylation pharmacokinetics/pharmacodynamics
Онлайн доступ:	https://www.mdpi.com/1999-4923/15/6/1668
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