Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis.

BACKGROUND:A host defense function for Alkaline phosphatases (ALPs) is suggested by the contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide (endotoxin) in animal models in vivo and the elevation of ALP activity following treatment of human cells with inflammatory stimuli in vi...

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Detalhes bibliográficos

Principais autores:	Matthew Pettengill, Juan D Matute, Megan Tresenriter, Julie Hibbert, David Burgner, Peter Richmond, José Luis Millán, Al Ozonoff, Tobias Strunk, Andrew Currie, Ofer Levy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2017-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC5407836?pdf=render
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