Inhaled sedation versus propofol in respiratory failure in the ICU (INSPiRE-ICU2): study protocol for a multicenter randomized controlled trial

Abstract Background Patients undergoing invasive mechanical ventilation often require pharmacologic sedation to facilitate tolerance of this life-sustaining intervention, but sedatives currently used in routine care have substantial limitations. Isoflurane is an inhaled volatile anesthetic with phar...

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Auteurs principaux:	Brian O’Gara, Alexis L. Serra, Joshua A. Englert, Alisha Sachdev, Robert L. Owens, Steven Y. Chang, Pauline K. Park, Daniel Talmor, Ida Sverud, Peter Sackey, Jeremy R. Beitler
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-03-01
Collection:	Trials
Sujets:	Inhalation anesthetic Isoflurane Propofol Moderate sedation Deep sedation Respiratory failure
Accès en ligne:	https://doi.org/10.1186/s13063-025-08791-0
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