Molecular profiling of tissue biopsies reveals unique signatures associated with streptococcal necrotizing soft tissue infections

Necrotizing soft tissue infections (NSTIs) are caused by a single pathogen such as Streptococcus pyogenes or by multiple bacterial species. Here, the authors integrate microbial community profiling with host and pathogen transcriptional analysis in patient biopsies, and identify an interferon-relate...

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Detalhes bibliográficos

Principais autores:	Robert Thänert, Andreas Itzek, Jörn Hoßmann, Domenica Hamisch, Martin Bruun Madsen, Ole Hyldegaard, Steinar Skrede, Trond Bruun, Anna Norrby-Teglund, INFECT study group, Eva Medina, Dietmar H. Pieper
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2019-08-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-019-11722-8
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