Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity

Background Altered regulation of many transcription factors has been shown to be important in the development of leukemia. TWIST2 modulates the activity of a number of important transcription factors and is known to be a regulator of hematopoietic differentiation. Here, we investigated the significa...

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Principais autores:	Shabnam H. Thathia, Stuart Ferguson, Hannah E. Gautrey, Sanne D. van Otterdijk, Michela Hili, Vikki Rand, Anthony V. Moorman, Stefan Meyer, Robert Brown, Gordon Strathdee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2012-03-01
coleção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/6239
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