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BDNF-dependent nano-organization of Neogenin and the WAVE regulatory complex promotes actin remodeling in dendritic spines

Summary: Synaptic structural plasticity, the expansion of dendritic spines in response to synaptic stimulation, is essential for experience-dependent plasticity and is driven by branched actin polymerization. The WAVE regulatory complex (WRC) is confined to nanodomains at the postsynaptic membrane w...

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Auteurs principaux: Belal Shohayeb, Kai Sempert, Tristan P. Wallis, Frédéric A. Meunier, Nela Durisic, Elizabeth A. O'Brien, Cecilia Flores, Helen M. Cooper
Format: Artigo
Langue:Inglês
Publié: Elsevier 2024-09-01
Collection:iScience
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2589004224018467
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