Single cell analysis identifies distinct CD4 + T cells associated with the pathobiology of pediatric obesity related asthma
Abstract Pediatric obesity-related asthma is characterized by non-atopic T helper 1 (Th1) inflammation and steroid resistance. CDC42 upregulation in CD4 + T cells underlies Th1 inflammation but the CD4 + T cell subtype(s) with CDC42 upregulation and their contribution to steroid resistance are not k...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2025-02-01
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| Colección: | Scientific Reports |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1038/s41598-025-88423-4 |
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