Alpha-synuclein inclusions reduced by PIKfyve inhibition in Parkinson disease cell models
Objective: Parkinson's disease (PD) pathophysiology is associated with a progressive loss of dopaminergic neurons in the substantia nigra and accumulation of insoluble inclusions of misfolded alpha-synuclein. In this study, we used a neuroblastoma-derived cell model overexpressing a pro-aggregation...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2025-10-01
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| Serie: | Neurobiology of Disease |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S0969996125002694 |
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