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Significance of Wnt/β-Catenin Signal Activation for Resistance to Neoadjuvant Chemoradiotherapy in Rectal Cancer

Although a therapeutic response to neoadjuvant chemoradiotherapy (NACRT) is important to improve oncological outcomes after surgery in patients with locally advanced rectal cancer, there is no reliable predictor for this. The Wnt/β-catenin signal is known to be crucial for the tumorigenesis of color...

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Principais autores: Shoji Miyako, Takeru Matsuda, Yu-ichiro Koma, Takahiro Koide, Ryuichiro Sawada, Hiroshi Hasegawa, Kimihiro Yamashita, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Shingo Kanaji, Taro Oshikiri, Yoshihiro Kakeji
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-01-01
Serier:Biomedicines
Fag:
rectal cancer
β-catenin
NACRT
Online adgang:https://www.mdpi.com/2227-9059/11/1/174
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