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Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Patients

Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy. Limited access of drugs to tumor cells is one reason for such grim clinical outcomes. A driving force for therapeutic delivery is interstitial fluid flow (IFF...

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Principais autores: Krishnashis Chatterjee, Naciye Atay, Daniel Abler, Saloni Bhargava, Prativa Sahoo, Russell C. Rockne, Jennifer M. Munson
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-02-01
סדרה:Pharmaceutics
נושאים:
glioblastoma (GBM)
DCE-MRI
interstitial flow
convection
diffusion
Cancer Imaging Archive
גישה מקוונת:https://www.mdpi.com/1999-4923/13/2/212
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