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Excessive aggregation of membrane proteins in the Martini model.

The coarse-grained Martini model is employed extensively to study membrane protein oligomerization. While this approach is exceptionally promising given its computational efficiency, it is alarming that a significant fraction of these studies demonstrate unrealistic protein clusters, whose formation...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Matti Javanainen, Hector Martinez-Seara, Ilpo Vattulainen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2017-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC5683612?pdf=render
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