Mapping the landscape of managed entry agreements: a systematic review of global frameworks, system-level components, and implementation challenges

BackgroundManaged Entry Agreements (MEAs) are pivotal for enabling access to innovative pharmaceuticals while mitigating financial risk and addressing evidence uncertainty. Despite conceptual acceptance, the essential requirements for their design and implementation are poorly documented, posing a c...

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Autors principals:	Hussain Abdulrahman Al-Omar, Asma Abdulaziz Almuhsin, Lolwa Hamad Almudaiyan, Amal Hassan Al-Najjar, Laila Carolina Abu Esba, Hind Almodaimegh, Jehan Alamre, Consuela Cheriece Yousef, Mansoor Ahmed Khan, Khalid AlYahya, Esraa S. Altawil, Abdualmajeed Saad Binjumayah, Faisal Awwadh Alharbi, Sultan Tawfiq AlShurbaji, Fatma Maraiki, Jaime Espín, Rosanna Tarricone, Panos Kanavos
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-04-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	challenges framework governance health system implementation managed entry agreements
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1803870/full
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