Proteomic Characterization of Synaptosomes from Human Substantia Nigra Indicates Altered Mitochondrial Translation in Parkinson’s Disease

The pathological hallmark of Parkinson’s disease (PD) is the loss of neuromelanin-containing dopaminergic neurons within the substantia nigra pars compacta (SNpc). Additionally, numerous studies indicate an altered synaptic function during disease progression. To gain new insights into the molecular...

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Detalhes bibliográficos

Principais autores:	Sarah Plum, Britta Eggers, Stefan Helling, Markus Stepath, Carsten Theiss, Renata E. P. Leite, Mariana Molina, Lea T. Grinberg, Peter Riederer, Manfred Gerlach, Caroline May, Katrin Marcus
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-12-01
coleção:	Cells
Assuntos:	synaptosomes proteomics Parkinson’s disease substantia nigra pars compacta mitochondrial pathology mitochondrial translation
Acesso em linha:	https://www.mdpi.com/2073-4409/9/12/2580
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