Circulating pro-angiogenic cells are preserved despite myocardial angiogenic signal deficits in HFpEF model

Abstract Heart failure with preserved ejection fraction (HFpEF) has no cure, and microvascular dysfunction is a major contributing factor to its pathophysiology. Circulating endothelial progenitor cells (EPCs) and Angiogenic T (i.e., Tang) cells which support vascular repair are deficient in clinica...

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Detalhes bibliográficos

Principais autores:	Pallavi Shrivastava, Rukayat A. Raji, Abdallah Jwayyed, Huijing Xia, Marian E. Okon, Ifechukwude J. Biose
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-04-01
coleção:	Scientific Reports
Assuntos:	HFpEF ZSF-1 obese rat Endothelial progenitor cells Angiogenic T-cells Tang cells Myocardial angiogenesis
Acesso em linha:	https://doi.org/10.1038/s41598-026-47557-9
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