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Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery

The ESCRT pathway is crucial for membrane remodelling in eukaryotes. Here, Hatano et al. explore the phylogeny, structure, and biochemistry of homologues of the ESCRT machinery and the associated ubiquitylation system in Asgard archaea, the closest living relatives of eukaryotes.

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Autori principali: Tomoyuki Hatano, Saravanan Palani, Dimitra Papatziamou, Ralf Salzer, Diorge P. Souza, Daniel Tamarit, Mehul Makwana, Antonia Potter, Alexandra Haig, Wenjue Xu, David Townsend, David Rochester, Dom Bellini, Hamdi M. A. Hussain, Thijs J. G. Ettema, Jan Löwe, Buzz Baum, Nicholas P. Robinson, Mohan Balasubramanian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2022-06-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-022-30656-2
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